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KMID : 0882419930450020255
Korean Journal of Medicine
1993 Volume.45 No. 2 p.255 ~ p.260
Pseudo-Bartter's Syndrome with Nephrocalcinosis Caused by Long-Term Surreptitious Furosemide Ingestion
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Abstract
30-year-old married woman showed hypokalemic metabolic alkalosis, normotensive hyperreninemia, hyperaldosteronism and a high urinary sodium and chloride level. She was thought have Batter's syndrome because she denied taking diuretics. But all
the
five
tests of urine for furosemide by high performance liquid chromatography (HPLC) gave positive results. On being confronted with the results of urine analysis showing the presence of furosemide, she did admit to the taking of furosemide for 11
years.
Renal radiologic studies including intravenous pyelography, ultrasonography, and computed tomography showed medullary nephrocalcinosis.
This case is unique in that nephrocalcinosis have been related to long term furosemide
ingestion in adults and we concluded that this apparent case of Bartter's syndrome with
nephrocalcinosis was caused by long term surreptitious diuretic ingestion and suggest that
this may occur more frequently than is generally appreciated.
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